The final choice relapsed on the screw motor, for it is the best compromise in terms of efficiency, lubrication and reliability.
The formulation of nonviral vectors composed of cationic polymers and anionic nucleic acids is constrained by the compromise of high transfection efficiency, which is oftentimes achieved only at the price of high cytotoxicity.
The poor pharmacokinetics, side effects and particularly the rapid emergence of drug resistance compromise the efficiency of the clinically used anti-HIV drugs.
Adapted scenarios have been created for 22 facilities to identify deficiencies in OR management that compromise the efficiency of use of OR time.
Although the lack of time constraints in the decision period and the lack of jitter may compromise the efficiency of this task for fMRI, using TD and fictive errors derived from model-based approaches as parametric modulation could potentially increase the efficiency compared with contrast-based approaches.
Because binding of RNAP to misplaced sites could compromise the efficiency of transcription, natural selection for the optimization of gene expression should regulate the distribution of DNA motifs capable of RNAP-binding across the genome.
Thus, its association with DNA repair intermediates generated during the processing of alkylated bases might well compromise the efficiency of base excision repair.
Possibly, the express heating/cooling default settings of current generation thermal cyclers may compromise the efficiency of the GP5+/GP6+ PCR assay as developed using early generation machines [ 6, 7].
Alternatively, since AR is associated with the DNA replication machinery ([ 75]; S. Murthy, U. Bai and G.P. Reddy; manuscript in preparation), and since telomere DNA replication utilizes the DNA replication machinery [ 82], it is conceivable that AR inactivation may compromise the efficiency of the DNA replication machinery during the replication of fragile sites in telomeres.
Competitive asymmetries, in turn, may result in a more pronounced inhibition of juveniles, or even adult females, which at some point would seriously compromise the efficiency of the supplementary feeding programme for such target sex and age classes.
