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An oligonucleotide comprising Sequence ID No. X. "A gene comprising Sequence ID No. X".
The high interest in this druggable protein family triggered the generation of a large pool of data comprising sequence, structure, bioactivity, and mutation data.
Five matching mammoth genome sequences were found, comprising sequence coverage of about 50% (714/1434 bp).
Klebsiella pneumoniae clonal group (CG) 258, comprising sequence types (STs) 258, 11, and closely related variants, is associated with dissemination of the K. pneumoniae carbapenemase (KPC).
Briefly, genomic sequence in the form of genomic clones (mostly BACs) is analysed through an automated pipeline comprising sequence similarity searches against peptide and nucleotide sequence databases and analysis for repeats, protein domains, CpG islands and gene predictions.
To test this idea, we knocked in spacers, comprising sequence already present in the second intron of the BU-1 locus, to position the +3.5 G4 motif a further 500, 1,000 and 2,500 bp away from the TSS.
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In order to directly detect nucleic acid polymers, we have designed biosensors comprising sequence-specific DNA binding proteins tethered to split-reporter proteins, which generate signal upon binding a predetermined nucleic acid target, in an approach termed SEquence-Enabled Reassembly (SEER).
One CrtI lineage comprises primarily proteobacterial sequences, with sub-clades comprising sequences from proteorhodopsin-producers, bicyclic and linear xanthophyll-producing Proteobacteria.
They obtained two major lineages of rhodopsin evolution, one comprising sequences from haloarchaea and fungi and another proteorhodopsins.
Similarly, mutation of a GCGGC sequence centered at position −113 abrogated GST-E2F1 binding to a probe comprising sequences from −135 to −100 (Fig. 4B, C).
Mutation of a GCGCG element centered at position −158 in a probe comprising sequences from −168 to −130 abolished GST-E2F1 binding (Fig. 4B, C).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com