A GA comprises parameters of its major operators which are crossover, mutation, and elitism.
The model for PSA dynamics comprised parameters for baseline PSA (23.2 ng/ml, relative standard error (RSE) 16.5%), growth rate (0.00879 day−1, RSE 12.6%), drug effect (0.241 µg·h·l−1 day−1, RSE 32.6%), and resistance development (0.0113 day−1, RSE 44.3%).
Second, after increasing the number of parameters that could be included in each equation, we had to deal with the problem that some equations comprised parameters that were correlated with each other (though not with r > 0.98, as these were already averaged together), which increased the risk of over-fitting without being very informative.
The likelihood of the observed incidence and prevalence was computed for 2.28 million sets of randomly drawn parameter values, comprising 40 parameters each (Table 1).
The original Kuznetsov model comprise parameter constellations for which there is a stable steady state of small tumour amounts controlled by a stimulated immune system.
The first group comprises parameter settings that are instrument dependent or a property of the acquired chromatograms (e.g. maximum output level of the mass spectrometer or average chromatographic peak width).
On a larger scale three major clusters can be observed from top the first one comprising seven parameters (Mg2+, EC, HCO3 −, TA, CO3 2−, Na+, K+), second one comprising five parameters (Ca2+, TH, TDS, SO4 2−, Cl−) and the third one of four parameters (PO4 3−, Fe2+, F−, pH).
However, the systems comprising more parameters would still be expected to be measured with greater reliability, and the individual parameters may also differ with respect to physiological stability and reliability of measurement.
This initial study led to the development of an "optimum" RuC mix, comprising mix parameters leading to the highest workability and strength at all rubber contents.
A linear transfer function model comprising 4 parameters is used to describe the post-prandial breakfast excursions of a group of 10 type 1 diabetes patients who are treated with multiple daily insulin injections.
