The fibre loaded with ciprofloxacin and diclofenac sodium was comprised of alginate and glycerol crosslinked with barium cations.
This study aimed to formulate a polymeric fibre device (PFD) comprised of alginate, glycerol, and barium chloride with ciprofloxacin and diclofenac sodium incorporated as the antimicrobial and anti-inflammatory model, respectively.
A composite delivery system comprised of alginate-poly-l-lysine-alginate (APA -microencapsulated Epo-secreting myoblAPA -microencapsulated (DXM)-releasing poly(lactic-co-glycolic acid) (PLGA) microspheres was implanted in the subcutaneous space of Balb/c myoblasts45 dand.
In accordance with the factorial matrix, gelispheres were formulated by titrating a combination polymeric solution comprised of sodium alginate, pectin and/or cellulose acetophthalate into an inducer solution (crosslinking agent) consisting of calcium and/or acetate ions.
The method involves the formulation of two-component kits comprised of soluble alginate and insoluble alginate/gelling ion particles.
Two film forming solutions were prepared by dispersing the dry materials (1% w/w sodium alginate or a blend comprising of 0.5% w/w sodium alginate and 2.0% w/w whey protein concentrate) in distilled water at 25 °C under agitation for 1 h to allow full hydration.
A formulation comprising of 4.38% (w/v) alginate, 1.39% (w/v) chitosan and 6.82% (w/v) calcium chloride was found to fulfill requisites of an optimum formulation.
The present paper describes, for the first time, animal experiments in which two types of new antiadhesive materials comprising sodium alginate with and without a small amount of calcium gluconate solution had superior antiadhesive effects against PGA-induced adhesions to fibrin glue, the conventional antiadhesive material in the clinical setting [ 22, 23].
3D alginate culture, comprising of naturally occurring non-toxic anionic polysaccharides, has been used to encapsulate a wide variety of cell types for tissue engineering and tumor research [ 4- 6].
Here, we demonstrate a strategy that supports sustained self-renewal of hESCs in a three-dimensional porous natural polymer scaffold, comprised of chitosan and alginate, without the support of feeder cells or conditioned medium.
