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Because the components comprising inflammation are very numerous and interacting across many pathways, without strong a priori evidence it is difficult to choose a handful of candidate genes to fully cover the potential genetic risk factors contributing to the inflammatory component of a particular disease.
In this study, we have shown that in CIA, major histopathological changes, comprising inflammation as well as bone formation and ankylosis, occur within the first two weeks after the inflammatory symptoms become clinically apparent in a joint.
Atherosclerosis is a complicated process comprising inflammation, accumulation of collagen matrix and aberrant DNA methylation.
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The major pathological hallmarks of multiple sclerosis (MS) comprise inflammation, demyelination with associated gliosis and axonal damage, which most likely correlates with persisting disability.
The possible mechanisms by which colorectal neoplasms arise in subjects with MetS comprise inflammation, insulin resistance and oxidative stress [ 18].
The skin involvement in SSc is a complex process comprising ischaemia, inflammation and fibrosis and it is difficult to distinguish between thick, hard or hidebound skin.
A wound repair is a complicated and dynamic process which comprises of inflammation, angiogenesis, and tissue formation/remodeling [2].
As such, these protumorigenic inflammatory cells comprise "bad inflammation," in contrast to components of the inflammatory infiltrate that represent an antitumorigenic force and, therefore, constitute "good inflammation" [ 9].
The clinical features of patients with chronic periodontitis comprised gingival inflammation and bleeding and periodontal pocket formation from alveolar bone loss as evaluated by the radiography.
As a main indication the disease comprises chronic inflammation of pheripheral joints, resulting in progressive destruction of articular cartilage and bone [ 2].
The hypothesized biological pathways comprise systemic inflammation and placental oxidative stress (Redman and Sargent 2003; Sibai et al. 2005; Terzano et al. 2010).
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