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As well as alterations in trabecular bone, comprising increased trabecular BMD, HBM cases showed a marked cortical bone phenotype, comprising increased cBMD, TBA, CBA and cortical thickness (Fig. 3).

In the placebo group, 5/61 (8%) reported adverse events comprising increased short term pain during or after the treatment session.

After MSC intervention, the irradiated mice survived longer than controls, and the epithelium showed hypertrophic villi, comprising increased numbers of proliferative cells and fewer apoptotic cells in the crypts.

Recently, a number of investigations have demonstrated that the involvement of a ductular reaction (DR), which is a reactive lesion at the portal tract interface comprising increased bile ductules with an accompanying complex of stromal and inflammatory cells, has been implicated in the pathogenesis of progressive fibrosis, regeneration and hepato-carcinogenesis in chronic liver disease [ 5, 6].

Host CMI responses in cna1-inoculated mice were observed to be dose-dependent, and comprise increases in pulmonary macrophages and CD4+ T lymphocytes.

The morphological changes of the root system triggered by HS comprise increases of lateral root formation sites, root hair density and length [21], as well as overall surface area available for bacteria attachment (Fig. 2B).

Further, socio-economic impacts triggered by the invasion of P. juliflora comprised increased health risks due to higher exposure to predators and malaria, constrained access to water points and the emergence of new fatal animal diseases like "Harmaku", resulting from cytotoxins damaging the neurons of the intoxicated animals (Silva et al. 2007).

Since social insect colonies tend to progressively comprise increasing numbers of individuals, in cases where nest size is volume-limited (such as in the cavity-nesting B. terrestris) [3], the density effect (i.e. the number of individuals per unit area) cannot be disentangled from the group-size effect (i.e. the number of individuals).

The functional changes comprise increased synthesis of inhibin, β-casein and other milk-related bioactive peptides.

The main objective during resuscitation from severe hemorrhage comprises increasing oxygen delivery to vital organs without concomitant augmentation of bleeding.

Adverse events comprised increased shortness of breath (5), pain (5), arrhythmia (3), bronchospasm (1), and thoracic haematoma (1).

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