The phrase 'comprises the backbone' is correct and usable in written English.
You can use it when you want to describe the essential elements of a complex concept or system. For example, you could write, "This course comprises the backbone of our curriculum."
A three-tiered model comprising the backbone layer, distribution layer, and access layer is used.
Recently, we reported on a series of short amphipathic α-helical peptides, comprising the backbone sequence (LLKK 2, with the ability to kill susceptible and drug-resistant Mycobacterium tuberculosis.
Within the Middle module, the subunits comprising the backbone scaffold (Med7-21-4-9) are alocalizedelocalizedzed.
Corticosteroids comprise the backbone of asthma therapy and act to reduce inflammation through both gene activation and suppression 43.
Ontologies now comprise the backbone of biomedical informatics, with dedicated institutions such as the National Center for Biomedical Ontology (NCBO) [ 30] and resources such as the BioPortal [ 31].
Seven Cδ domains comprise the backbone of many bony fish delta chains, wherein a wide range of domain organization within fish lineages is observed.
The number of ORFs, which comprised the backbone sequence of Shigella spp. strains used in this study, was 1955 (include 12 ORFs which were not present in MG1655), which was less than the number cited in previous reports [ 10, 12].
Based on the above evidence, it can be deduced that the β-sheet comprises the skeleton and backbone of the enzyme, while the α-helices or other secondary structure elements, e.g. turns, are required for the catalytic reaction.
The expression plasmid of the PSMAxCD3 diabody for co-secretion of the two hybrid scFvs was constructed by ligation of the Bgl II/XbaI restriction fragment from pHOGCD-3-PSMA comprising the vector backbone and the Bgl II/Xba I fragment from pHOG-PSMACD-3 (Fig. 1c).
It is well known that osmolytes induce protein folding due to solvophobic effects on peptide backbone, and the fact that protein backbone comprises the most numerous functional groups of proteins, osmolyte-induced conformations result in native-like functional species [21].
