The second comprises damage-probability curves, which provide information on the distribution of the risks, taking into account whether they originate from frequent floods with slight consequences or from exceptional floods with major consequences.
Scanline surveys along the ore-controlling fault zones show an internal structure that comprises a damage zone, a breccia zone with clasts that have become rounded, and a breccia zone with lenticular clasts, and this complex architecture was formed during at least two compressional substages of deformation.
The jury awarded Mr Ernst's widow $253m, mainly comprising punitive damages, having decided that Merck was well aware of the potential risks associated with the drug.
The DDR is a complex network of proteins, comprising DNA damage recognition, signal transduction, transcriptional regulation, cell cycle control and DNA repair.
Variants of the histone H2A family (the largest among histone classes family) are the most diverse in sequence and exhibit distinct functions, comprising DNA damage repair, transcriptional regulation, cell cycle control, and chromatin condensation [ 62], [ 63].
Mechanisms of cardiotoxicity by antiblastic drugs comprise cellular damage, with the formation of free oxygen radicals and the induction of immunogenic reactions with the presence of antigen presenting cells in the heart [ 4].
The mammalians response to DNA damage comprises a highly co-ordinated, yet complex network of proteins that have been categorized as sensors, signal transducers, mediators and effectors of damage and repair.
With the help of a composite damage model comprising both continuum damage mechanics model and surface-based cohesive contact model, a good correlation between the experimental and numerical results is obtained, and therefore validates correctness and effectiveness of the proposed mechanical model.
The impact assessment method developed by Pfister and colleagues comprises (amongs others) two damage assessment models which describe the cause-effect chains of water consumption leading to malnutrition induced human health damage and ecosystem damage resulting from reduced net primary production (Pfister et al. 2009).
NCT01547910 Non-alcoholic fatty liver disease (NAFLD) comprises spectrum of liver damage that ranges from simple steatosis through steatohepatitis (NASH), fibrosis to cirrhosis, end-stage liver disease and occasionally hepatocellular carcinoma.
Alternatively, the observed enhanced chromosomal radiosensitivity may also result from a less efficient G2/M checkpoint, as it has been shown that G2 checkpoint abrogation comprises repair of chromosome damage and that defects in the G2/M checkpoint are associated with increased cancer risk (Terzoudi et al, 2005; Wu et al, 2005; Zheng et al, 2005).
