The SAM comprises items assessing self-reported episodic autobiographical, semantic, and spatial memory, as well as future prospection.
The GMS comprises measures assessing psychiatric symptoms of organicity, depression, anxiety and psychosis, with ratings for each derived using the AGECAT algorithm.
The MMSE consists of 30 items comprising subscales assessing orientation, word registration, attention (via a serial sevens or spelling task), word recall, and language.
The Work and Social Adjustment Scale - WSAS [ 18] is a self-report measure comprising subscales assessing functional impairment in the areas of work, home management, social leisure activities, private leisure activities (eg reading, gardening, etc) and close relationships.
The following secondary outcomes will also be assessed; these comprise the sub-components of the TPB [ 20]: attitudes, perceived behavioural control and subjective norms.
Specific exclusion criteria for this study comprised: atopy assessed by a screening test (see below), smoking, current respiratory tract infections, and anti-inflammatory drug intake assessed by questionnaire.
The CAMPHOR is a PH-specific measure and comprises three scales assessing impairments (symptoms), activity limitations (functioning) and quality of life (QoL).
Signs with a significantly lower hazard rate compared to controls were predominantly displayed by BSE-negative, inoculated animals and mainly comprised signs assessed by observations.
The BASFI comprises 10 items assessing physical function over the preceding week [ 25].
33 The SMFQ comprises 13 items assessing depressive symptoms rated on a 3-point scale.
