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Strikingly, almost all the proteins whose association with Ku was diminished upon MLN4924 treatment comprised factors associated with the 26S proteasome, as well as the segregase/unfoldase VCP (valosin containing protein; also known as p97) that targets ubiquitylated proteins to dissociate them from molecular assemblies, frequently promoting their proteasomal degradation (Meerang et al., 2011).
Among the items of each of the three options, only the category of "Necessary" comprised factors representing the correct diagnosis of Autism.
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The first factor, provisionally entitled "Clinical care and service management" comprised Factor 2 (reflective practice) from the original factor analysis [ 8] and much of factors 3 (decision making) and 4 (technical and administrative procedures) [ 8].
It comprises factors related to applied knowledge and the materials and machines used in the production of goods and services.
A cognitive model (CM) of the decision problem consists of a directed graph that comprises factors, and connections between the factors.
Turnaround context, as summarized under the umbrella of contingency theory, comprises factors that are exogenous to the immediate scope of managerial actions (Pettigrew 1987).
The latter comprises factors which drive staff out of the public sector.
Our interactome data might therefore comprise factors involved in these functions as well.
The first level comprises factors extrinsic to the wound itself, while the second level consists of intrinsic factors.
The third group comprises factors involved in hemostasis, inflammation and endothelial function (e.g. [ 53, 111, 112]).
The second group comprises factors involved in hemostasis, inflammation and endothelial function (e.g. [ 36– 38]. The third group, and currently a major focus, covers genetic factors in these areas.
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