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The meiotic phenotypes comprised defects early in prophase which presented as discontinuities in the thread-like appearance characteristic of leptotene and zygotene stages.
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In up to 85% of cases, it results from thyroid dysgenesis, a condition comprised of defects in the differentiation, migration or growth of thyroid tissue.
The timing of maximal PANS1 expression during meiosis therefore appears to precede the onset of the mutant phenotype (comprising defects in centromere organization starting late in meiosis I and extending to interkinesis during the second meiotic division).
However, the surface area does not commensurately increase, indicating the inaccessible microporosity to predominantly comprise surface defects and roughness that are removed on heat treatment or activation.
Notably, some of the clinical features associated to deregulated ERα-signaling pathways are included in the large spectrum of KS phenotypes, comprising immunological defects and cardiac anomalies [Deroo and Korach, 2006].
A severely comminuted fracture forms a "contained defect" comprised of fracture fragments with reduced viability.
Children born in Western Australia from 1980 1999 with a major birth defect comprised 4.6% of live births but 12.0% of non-birth hospital admissions from 1980 2000.
SCD circumvents by design the curse of dimensionality of the variable space that renders traditional ODE-based RT approaches inefficient when handling complex defect population comprised of multiple (more than two) defect species.
The pinA pinB double mutant phenotype comprises class II defects, but more-severe defects were not observed.
A common feature of the worn MLG was the sliding induced defects which comprised of edge fracture, fragmented/bent graphene stacks compared to pristine graphene and disordered regions between them.
Defects mainly comprised exencephaly (82%), in which the cranial neural folds persistently failed to close (Fig. 4).
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