Sentence examples for comprise the activation of from inspiring English sources

Both pathways comprise the activation of caspase cascades, leading to cell death.

Indeed, hemorrhagic shock precipitates inflammatory cascades that comprise the activation of stress transcriptional factors and up-regulation of cytokines synthesis [ 9, 10] leading to multiple organ failure [ 10].

Over the past decade, multiple clock genes have been identified, and it is now generally accepted that the generation of circadian rhythms is based on transcription-translation feedback loops comprising the activation of multiple clock genes.

In case of overactivation of these receptors, the excessive Ca2+ influx into the cell induces a cell death cascade, which comprises the activation of proteases, lipases and other enzymes leading to cell lysis [ 7].

These findings do not clarify the complete scenario of events following inoculation but support the concept that IL-12 and IL-18 are able to induce a broad spectrum of effects, comprising the activation of microglia as showed by the increased cytokine production and especially by increased immunoreactivity to F4/80 in brain tissues.

Mechanisms for regulation of NF-κB activity comprise inhibiting the activation of IKK complex, inhibiting the phosphorylation of IκB, preventing the degradation of IκB, blocking the migration of NF-κB to nucleus, and decreasing the DNA binding activity of NF-κB.

Significant insights into this mechanism were provided by the recent publication of structural, biochemical and functional data on the N-terminal domain of Cdc13 (Cdc13N:OB1), a domain thought to comprise the telomerase activation domain of the protein.

Both migraine and TACs are believed to share a common pathophysiology comprising of the activation of the trigeminovascular system and involvement of neuroactive peptides such as calcitonin gene-related peptide (CGRP), vasoactive peptide (VIP) and glutamate [14].

These transcription activation rates comprise the "rules of integration at the promoter," and describe how the promoter integrates common transcriptional inputs.

Activation of these pathways ultimately leads to activation of transcription factors and cell activities that comprise the response of a given cell to mechanical events.

The cellular events comprise inflammatory activation of Schwann cells and invasion of various types of immune cells, including macrophages, that produce cytokines and chemokines.