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Thus, amino acids that comprise disordered regions, such as random coils, are more likely to be under positive selection than expected from their proportion in the proteins, compared with the residues in helices and β-structures which are subjected to less positive selection [ 68].
The model char structures comprise disordered and buckled graphitic sheets containing a small percentage of interstitial diamond-like atoms between the sheets.
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It appears that what we currently call "schizophrenia" may comprise disorders with quite different trajectories.
Autism spectrum disorders (ASDs) comprise autistic disorder, Rett's disorder, Asperger's disorder, and pervasive developmental disorder not otherwise specified (PDD-NOS) in DSM-IV.
Minor mood disorders comprise depressive disorders not otherwise specified, dysthymia, cyclothymia and adjustment disorders.
The underlying causes of FADS are diverse, comprising disorders of the central nervous system, musculature, and connective tissue, as well as extrinsic factors such as maternal drug use or illness or foetal crowding.
One of the most studied BRCA1 isoform has 1863 amino acids and comprises a long highly disordered central region flanked by ordered domains at the two termini.
Monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) comprise heterogeneous disorders with incompletely understood molecular defects and variable clinical features.
Inflammatory myopathies comprise heterogeneous disorders.
Because somatic or psychiatric diseases have not been formally excluded, the classification of CF could comprise numerous disorders in addition to CFS.
The inflammatory arthritides, including rheumatoid arthritis (RA) and psoriatic arthritis (PsA), comprise autoimmune disorders characterised by chronic joint inflammation, immune cell infiltration to the synovium, fibroblast-like synoviocyte expansion and destruction of cartilage and bone.
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