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Spatial biases comprise a major source of noise in microarray studies; revision of routine experimental practices and normalizations to account for these biases may significantly and comprehensively improve the quality of new as well as existing DNA microarray data.
The tumour cells, themselves, are a source of MMPs (Wright et al, 1994; Putnins et al, 1996), but a variety of evidences suggests that cells of the stromal tissue surrounding the tumour comprise a major source of tissue-destructive MMPs (Kataoka et al, 1993; Heppner et al, 1996; Declerck, 2000).
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In this regard, it is critical the public and policymakers refocus on and rein in exponentially-growing private sector debts as this comprises a major source of future financial instability.
Oxidative stress comprises a major source for DNA damage in post-mitotic neurons.
In human medicine, they comprise a large number of pathogens and provide a major source of antibiotics [ 1].
While Landry et al. considered pharmaceutical costs, and this study did not, this is not anticipated to be a major source of discrepancy as they comprised a relatively minor proportion of overall medical costs (approximately 1-21-2% 18].
Carbohydrates, mainly sugar additives comprising 48 98 mg/g per cigarette (Wang and Watson 2012), are a major source of acrolein in cigarette smoke (Roemer et al. 2012; Stevens and Maier 2008).
Tourism is a major source of income.
This is a major source of problems".
They are a major source of reaction in the region".
It's still a major source of pain and confusion.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com