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For example, this approach has led to the identification and isolation of many novel non-protein-coding RNAs (ncRNAs), which have been suggested to comprise a major component of the transcriptome that have novel functions involved in epigenetic regulation of the genome.
Network FFLs, initially described by Alon and colleagues, were shown to comprise a major component of the transcription networks in bacteria and yeast [ 63, 64].
Genes involved in cell proliferation have been shown to comprise a major component of many of the available gene expression signatures used to predict clinical outcome in breast cancer patients [ 11– 16].
Unsurprisingly, the laboratory costs (including test kit cost) were found to comprise a major component (>60%) of the total aggregated cost of careHPV screening and of the pathology tests (biopsy, ECC) (Table 1).
In vivo studies have demonstrated that the epidermis is characterized by a defined differentiation-dependent expression of Claudins (Cldns), a family of tetraspan membrane proteins that comprise a major component of TJ fibrils essential to the structure and function of TJs [ 2- 6].
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Fungi comprised a major component of the biota interacting with the granular substrates in all field sites (Fig. 3a d) and showed strong evidence of biomechanical weathering (Fig. 3b d).
α-Synuclein comprises a major component of Lewy bodies and Lewy neurites in DA neurons in the substantia nigra of patients with PD, and is a major constituent of other types of inclusions found in a group of diseases, collectively known as 'synucleinopathies' [11].
Collagen is a fibrous, extracellular, insoluble protein comprising a major component of connective tissues.
It is important that this is measured carefully because it comprises a major component of the QALY and inaccuracies will lead to inaccurate estimates.
The findings of this study suggest that Kv1.5, most likely co-assembled with Kvβ1 subunits, comprises a major component underlying the A-type K+ current in retinal arteriolar smooth muscle cells.
Because orthopaedic implants comprise such a major component of total episode cost, more value-sensitive selection by orthopaedic surgeons offers substantial opportunity for shared savings arrangements with patients and payors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com