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It is important, however, to note that none of theses phenotypes have been comprehensively replicated in experimental models that bear relevance to the heterozygous genetic background of FAD patients with PSEN mutations.
Similar(59)
"As with many other states, California will not be able to comprehensively replicate the corps' regulatory role in the foreseeable future because of its current budget crisis," the California EPA said in its comments on a rule change.
The expression and function of iron metabolism proteins in glia and neurons and the extent to which this iron regulatory system is replicated in in vitro models has been comprehensively described, followed by an appraisal of the inherent suitability of different in vitro and ex vivo models that have been, or might be, used for iron loading.
Although our results remain to be replicated in other cohorts, this is one of the few studies that comprehensively investigated the impact of the HLA-A gene on BD in relation to HLA-B*51.
The consistent DTI changes identified previously within the corticospinal tracts and corpus callosum (Kassubek et al., 2005; Filippini et al., 2010) have been replicated in many studies, and also related to clinical upper motor neuron signs (studies comprehensively reviewed in Turner et al., 2012).
He replicated it.
It cannot be replicated.
Will they be replicated?
It's easily replicated.
Mutations are replicated when the cell replicates.
Replicated by Raygduncan.
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