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The phrase "comprehensive transformation" is correct and usable in written English.
You can use it when referring to a thorough and complete change or overhaul. For example: "The company underwent a comprehensive transformation over the past year, introducing new products and technology in order to remain competitive."
Exact(12)
It is by undergoing the comprehensive transformation of industrialization that societies become modern.
With the emergence of increasingly sophisticated digital technologies, the practice of architecture is undergoing the most comprehensive transformation in centuries.
A large teaching hospital – with academic links, specialist treatments and looking at collaborating or merging with other organisations – will require a comprehensive transformation programme assessing and improving patient pathways and care plans, taking two or three years.
Low-income workers typically spend many hours and big chunks (often up to 20%) of their salaries on transport.The mayor, Parks Tau, speaks of "a comprehensive transformation of our spatial destiny and a break from our apartheid past".
This is the first study that reveals the comprehensive transformation map of bromine in SO4−⋅ based reaction systems, which should be taken into consideration when such technologies are used to eliminate contamination in real practice.
The 'socio-ecological' orientation of the Italian malaria campaign under Fascism, in which large-scale wetland reclamation for malaria control seemed to produce a comprehensive transformation of rural land and life, had a strong influence in Argentina, further entrenching environmental sanitation methods.
Similar(48)
Over the past few years, it has been engaged in a comprehensive digital transformation of how it provides services to its clients and customers.
These two applications were only the starting point for what would prove to be a comprehensive IT transformation – but the combination of CEO support and a manifest need for change gave Smoley the mandate he required.
This study of a formerly predominantly pastoral polity within a sub-national territorial entity of the Yemeni state that is presently entangled in a comprehensive communal transformation process emphasizes the changing interactional dynamics between Soqotran pastoralists' ecological praxes, environmental milieu and the pastoral herds.
Larock, R. C. Comprehensive Organic Transformations: A Guide to Functional Group Preparations 3rd edn (Wiley, New York, 2018).
However, wider citizen engagement and public discourse on comprehensive energy transformations appear somewhat stagnant.
More suggestions(16)
comprehensive conversion
thorough transformation
comprehensive mutation
comprehensive turnaround
broad transformation
extensive transformation
comprehensive shift
wide transformation
holistic transformation
comprehensive processing
comprehensive restructuring
comprehensive reorganisation
overall transformation
global transformation
complete transformation
sweeping transformation
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com