No structural data are available to confirm the HBV RT modeling, however, results were consistent with phenotypic analysis of comprehensive substitutions of each ETVr position.
The effects of comprehensive LNA substitution in PCR primers for amplification of human genomic DNA targets are presented in this report.
In contrast, our comprehensive nucleotide substitution study carried out on the whole mitogenome captures this information quite easily, provided that sufficient intraspecies and congeneric pairs are available for comparative analyses.
In this work, we provide a comprehensive study of substitution patterns along genes and their flanking regions in ten vertebrate species of the four taxa: primates, rodents, laurasiatheria and bony fish.
We have presented a comprehensive study of substitution rate variation in protein-coding sequences across the mammals, and shown that for mitochondrial synonymous sites, and for both synonymous and nonsynonymous sites in 6 nuclear loci, a substantial fraction of the between-lineage rate variation can be explained by aspects of life history.
These results demonstrate that this method is effective for the expression and analysis of mutated proteins with comprehensive amino acid substitutions at desired positions.
Streptavidin mutants with comprehensive amino acid substitutions at the Tyr83, Arg84, and Tyr54 positions were used for analyzing their biotin-binding activity by dot blot analysis.
In this work, a comprehensive study of Mn substitution for Sc is provided.
This study represents the most comprehensive collection of nrITS substitution rates to date.
In this work, we achieved a comprehensive comparison of mitochondrial substitution rate variation and mitochondrial diversity between birds and mammals.
