For data integration we map the interacting proteins from external or database specific identifiers to unique protein identifiers from UniProt and EntrezGene [ 49] to enable the combination of the different data sets to one comprehensive set of interaction data for each species.
Applying ANCEA to the active nodes identified by PPA will rapidly identify comprehensive sets of interactions for each active node and assign these interactions to specific pools of populations.
Current use of the word tends to refer to a comprehensive set of protein protein interactions.
When the goal is to identify a comprehensive set of regulatory interactions, the major challenge is to determine a suitable threshold to discriminate true binding sites from background noise.
NAEP, for example, employs a comprehensive set of two-factor interactions.
To estimate the overall false-negative rate of our Y2H screen, we made use of a comprehensive set of flagellar protein interactions, which we collected for a comprehensive study on bacterial motility [14].
We identify a comprehensive set of 243 gene interactions that includes the 27 standard pairwise tests used by Elena and Lenski.
To better understand the functioning of the various plant polyadenylation factor subunits, a comprehensive set of pair-wise interaction assays was conducted.
Based on these outcomes and the lack of systems biology research of inflammation in the specific context of MI, we set out to investigate a comprehensive set of inflammation-implicated protein interactions and its potential prognostic value post-MI.
In particular, transgenic and knock-in mouse lines with targeted anomalies in genes associated with autism and the development of a comprehensive set of rodent assays to assess social interaction, communication, and repetitive behaviors, have greatly enhanced our ability to test hypotheses about the causes of autism (Silverman et al. 2010).
To evaluate the quality of these inferred interactions we utilized a comprehensive set of P. falciparum specific coexpression data [ 39] to calculate Pearson's correlation coefficients r P for the inferred protein interactions.
