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The coverages of biological pathways can be increased with the incorporation of more biological processes and protein members, promoting more comprehensive pathways.
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The second approach is to provide a comprehensive pathway that provides a framework for understanding evolution prior to high school biology, or students' earliest evolution learning experience.
In a future study, the implicated regions in the present study will be chosen as seed regions for further effective connectivity analysis, in order to construct a comprehensive pathway model specifically accounting for CA in migraine.
To compensate for the anti-evolution exposure children receive prior to high school, a comprehensive pathway to understanding evolution and the nature of science is needed within the pre-high school curriculum.
We showed a comprehensive pathway signature and identified an adipogenic transdifferentiation signature in ccRCC.
To better understand the roles of these differentially expressed genes and their interactions in a complex biological system, a comprehensive pathway analysis is needed.
The Pathway Projector was implemented according to the aforementioned requirements, including the availability of a large-scale comprehensive pathway map, pathways from a wide variety of organisms, and searching and mapping capabilities.
A recent, comprehensive pathway resource from our lab, SignaLink, applies uniform curation rules to keep the levels of details to be identical in all examined pathways for C. elegans, D. melanogaster and humans [22].
These 3 proteins are all known members of the AMPK pathway (see Discussion) and, along with the findings that AMPK itself was activated in the MLL-rearranged cohort, form the basis of a comprehensive pathway derangement in MLL-rearranged patients (presented schematically in Figure 1B).
Comprehensive pathway annotation is the first step in mining the pathways underlying biological processes.
Here, we present FluMap, a comprehensive pathway map for IAV infections.
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