Sentence examples for comprehensive deletion from inspiring English sources

This is the first comprehensive deletion mapping by high density oligo-array of the 1p/19q co-deletion in oligodendroglioma tumors using a methodological approach superior to others previously applied.

We have performed a comprehensive deletion survey of 3p on more than 400 of lung, renal, breast, cervical and ovarian carcinomas (major epithelial cancers) using a defined set of markers, combining conventional LOH with quantitative real-time PCR (QPCR), comparative genomic and NotI microarrays hybridisations [1], [2], [3], [4], [5].

Pavur et al. [ 23] conducted a comprehensive deletion analysis of eEF2K, removing sections of roughly 50 residues from the protein.

We investigated the genetic basis for yeast, Saccharomyces cerevisiae, biofilm on solid surfaces in liquid medium by screening a comprehensive deletion mutant collection in the Σ1278b background and found 71 genes that were essential for biofilm development.

We also illustrate how a comprehensive deletion analysis can guide target selection for in vitro drug screening against asexual blood stages by deprioritizing genes that are functionally redundant in vivo.

We performed a comprehensive deletion survey of 3p in more than 400 of major epithelial cancer samples and identified two most frequently affected regions - LUCA at the centromeric and AP20 at the telomeric border of 3p21.3 [ 6- 10].

We obtained a series of nullisomic-tetrasomic wheat lines, each missing a single chromosome (nullisomic) substituted by an additional copy of a homoeologous chromosome (tetrasomic) [ 31, 32] as well as a comprehensive smaller deletion series of wheat lines [ 33].

While the computer time required for anything more than a comprehensive double-deletion study may be prohibitive, a many more knock-outs can be simulated in silico than can be performed in vivo.

We have constructed a comprehensive set of deletion mutants and systematically identified a clearly defined set of essential genes for Streptococcus sanguinis.

To identify previously unrecognized deleted genes or loci that can lead to MSI, we developed a functional genomics screen utilizing a plasmid containing a microsatellite sequence that is a host spot for MSI mutations and the comprehensive homozygous diploid deletion mutant resource for Saccharomyces cerevisiae.

The comprehensive yeast gene deletion strain collection has enabled high-throughput screens for phenotypic traits of yeast genes; however, many of the physiological conditions tested are not relevant to industrial or natural yeast environments (Scherens and Goffeau 2004).