"comprehensive changes" is a correct and usable phrase in written English.
It can be used to describe wide-ranging changes or reforms that affect many aspects of a given situation. For example, you might say: "The government outlined a plan to implement comprehensive changes to the healthcare system."
The comprehensive changes to the production and service sectors are leading to changing demands on the employees.
But under Florida's program, communities are making comprehensive changes.
Joe Lockhart, the White House spokesman, said that comprehensive changes at the Energy Department might be needed.
The campaign finance legislation, which would become effective after the November elections, would make the most comprehensive changes in the campaign finance law since the Watergate era.
Two big choices confront patients, politicians and policy makers: Should they pursue incremental changes in the health care system or comprehensive changes?
Mr. Obama also pledged during the 2008 campaign to pursue comprehensive changes to the immigration system in the country.
Today's most pressing injustices require comprehensive changes in the practices of the police, schools and employers — not simply responses to individual injuries.
"We need comprehensive changes so that the Security Council will be more representative of the 21st century," Mr. Morsi said in Arabic, speaking through an interpreter.
Three years later, the Emperor Guangxu set in motion the "Hundred Days' Reforms," comprehensive changes to education, the economy, the military and the bureaucracy aimed at modernizing China.
The governor said that New Jersey is the first state to call for comprehensive changes to prevent racial discrimination by officers, and the consent decree with the Justice Department will make her proposal a model for others to follow.
But only Congress can make comprehensive changes that would better balance the courts, and reform advocates note that thousands of low-level offenders remain in a system designed to keep them there.
