To provide a comprehensive analysis of the specific (A,A) pairs that showed significant evidence of selective interactions, we constructed two-dimensional maps of the statistical strength of covariation between all possible pairs of codons positions in HIV protease, for (A,A), (A,S) and (S,S) (Fig. 5).
Comprehensive analysis of one specific sORF, termed smORF2 even shows sequence conservation between yeast and human [ 6, 7].
We have developed high-throughput, sensitive, quantitative PSQ assays for DNA methylation at all characterized human imprinted loci and have produced the first comprehensive analysis of tissue specific methylation at human imprinted loci.
A key issue for the design of novel therapeutic strategies that target PKC isozymes is a comprehensive analysis of isozyme-specific signal transduction pathways in different cell types and the development of pharmacological and molecular tools that can distinguish between the various PKC and 'non-PKC' phorbol ester receptors.
This study represents a comprehensive analysis of sex-specific methylation patterns.
With the inclusion and careful analysis of all publicly available datasets, this study represents the most comprehensive analysis of sex-specific methylation patterns to date.
A variety of technologies such as hydrazide chemistry, lectin chromatography or bead-immobilized techniques have been used for comprehensive analysis of site-specific glycosylation [ 22- 26].
21 The information available is, however, largely from small-scale studies 21 and only a few studies are based on a comprehensive analysis of gender-specific vulnerabilities.
Given that current proteomics workflows achieve ∼30 to 40% mean sequence coverage at best, a comprehensive analysis of isoform-specific variation remains challenging.
We also carried out a comprehensive analysis of tissue-specific expression data generated by high-throughput microarray expression profiling experiments to discuss on the expression profile and possible functions of the soybean TCS genes.
