Sentence examples for comprehensive alterations from inspiring English sources

Kenilworth Castle was the centre of Leicester's ambitions to "plant" himself in the region, and he substantially transformed the site's appearance through comprehensive alterations.

High temperature cause comprehensive alterations in transcription, but application of auxin can block the transcriptional alterations, leading to the production of normal pollen grains, and the normal seed setting rate under increasing temperatures [ 74].

Recently, however, the Residential Management Council of the Real Estate Board of New York, with the help of the New York City Bar Association, developed a standardized, comprehensive alteration agreement that its creators say covers issues not addressed by the Blumberg form and clarifies others that are.

With the City Council scheduled to vote sometime in the next few months on a plan that would be, if adopted, the first comprehensive alteration of the city's zoning code since 1961, several organizations will conduct programs meant to explore the ramifications of the proposals.

All of the KV1 changes should be seen within the context of a wider and quite comprehensive alteration in the ion channel expression pattern as smooth muscle cells switch phenotype.

Here, we report the first comprehensive screening of alterations in DUB expression in nine human cancers.

Our data provide a comprehensive analysis of alterations in gene expression induced by HCV replication and reveal modulation of new genes potentially useful for selection of antiviral targets.

In the last years, microarray technology provided a comprehensive analysis of alterations in gene expression induced by HCV and revealed important processes of virus-host interactions [ 3- 7].

The information presented here serves as an update and augmentation to a previous comprehensive summary of alterations in the GALNS gene associated with Morquio A syndrome [Tomatsu et al., 2005b].

Although microarray technology has been employed to investigate gene expression changes following tendon injury [ 16], in tendinopathic tissue [ 17], in response to cyclical strain [ 18] or a single loading event [ 19], and effect of loading on tendon healing [ 20], no comprehensive analysis of alterations in gene expression with age has been undertaken in tendon.

A recent comprehensive survey of genomic alterations in gastric cancer identified change in FGFR2 expression as the most frequent change among the RTK (receptor tyrosine kinase)/ RAS family genes 49.