Therefore, we developed a strategy aimed at reaching consensus (i) with the MFTPA over the design of a consent process to support participants' comprehension of the purpose of the genetic study; and (ii) with fieldworkers and the community about the strategies available to combat further stigmatization as a result of the study.
For example, clearly worded, plain language, consent has been deemed acceptable in surveys that convey minimal to low risk and additional efforts to ensure complete comprehension of the purpose of the survey are not routinely made.
Differences in comprehension of study purpose between participants in the breast cancer study and the hypertension study may reflect the symbolic power attributed to a disease such as cancer, especially among the women with breast cancer in our study.
Results of analysis are described for: 1) beliefs about the meaning of voluntary participation; 2) beliefs about the need for seek permission from a husbands or community elders to participate in the study, and 3) comprehension of the purpose of the genetics of breast cancer study.
The survey and in-depth interview addressed topics associated with the process of consent including: participants' recall of being told about study goals, procedures, benefits and risks; comprehension of study purpose, voluntary participation, reasons for participating in the study, and permission of husbands or community elders in decisions to join the genetic study.
These cases suggested that comprehension of the study purpose and methods was complicated by the participant already having made a prostate cancer management decision and thus being a proxy user of the intervention.
In this paper, we report findings from a study examining factors associated with voluntary participation and comprehension of the study purpose among women involved in genetic epidemiological research on breast cancer in Ibadan, Nigeria, a large metropolitan city.
Breast cancer generally evokes greater concern among women everywhere than illnesses perceived as less threatening such as hypertension, and this could impact comprehension of the study purpose during the consent discussion.
Preventive misconception constitutes what may be an inappropriate motivation for participating in a clinical trial based on lack of comprehension of the trial's purpose or a sense of invincibility [ 44, 46, 47].
Religiosity may be associated with a clear sense of purpose and meaning comprehension.
People from such countries may feel that things "go right" regardless of their contribution which may possibly lead to having a less clear sense of purpose and meaning comprehension.
