Exact(13)
The filter formats may also retain a greater amount of contaminating compounds, yet all downstream analyses indicated that the DNA from each method was of high quality.
Actinomycetes produce a large variety of pharmaceutically active compounds, yet production titers often require to be improved for discovery, development and large-scale manufacturing.
For chemists everywhere these sort of studies reaffirms that there are areas of CP space still left to be explored, and many fascinating compounds yet to be made and many unusual properties to be discovered.
The presented detector development generally enables the chemical investigation of more short-lived and less volatile transactinide elements and their compounds, yet unreachable with the currently employed silicon-based solid state sensors.
For all libraries, pharmacophore-based similarity with the omission of two features yielded the largest number of similar compounds yet, these numbers drastically decreased when requiring complete matching, probably due to the large number of feature in this pharmacophore model (seven features).
Similarity could be assessed in several ways including: (1) pharmacophore-based which is particularly useful for identifying compounds with the same chemical features as the active compounds yet with new chemotypes or chemical scaffolds [8, 9], (2) fingerprints-based and (3) substructure-based.
Similar(47)
"There is nowhere near a safe picture really in this compound yet," said Al Jazeera's Sue Turton.
That is what New England Compounding's products would most likely be considered because the company was doing more than traditional compounding, yet had not obtained a new drug approval, something that large drug makers spend millions of dollars and years to get.
These movements are compound yet irreducible and work from core to extremity.
For example, if you're trying to be a drug discovery company, and have no lead compound yet, describe the target of that compound and your technological basis for finding it.
The approach knows nothing of the set membership of each compound, yet it shows a striking separation of the 1005 aryl-amines both by whether they are part of a drug company's tested compounds or from a literature Ames compilation.
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