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None of the six compounds with three components were found in either SureChEMBL or IBM SIIP.
Tripodal molecules are a group of compounds with three arms of donor groups.
As for four imide compounds with three alkyl substituent chains in the molecular skeleton, obvious differences were obtained.
In contrast to inhibitors having two aromatic rings, α-fluorination of compounds with three rings unexpectedly decreased the inhibitory activity.
The least number of significant media component interactions were noted for the acidic compounds with three and the greatest for the neutral compounds at seven, with again drug specific effects evident.
The DOE study noted clearly that its choice of biorefinery products was limited to the compounds with three to six carbon molecule chains (C3 C6) derived directly from the sugars in biomass.
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Many terrestrial species can perceive a range of common compounds with six or seven carbon atoms that are produced by all green plants as metabolic by-products.
Reaction of amides with acid chlorides or anhydrides produces imides, which are compounds with two carbonyl (CO) groups attached to the same nitrogen atom.
We also observed that oximation of carbonyl compounds with two carbonyl moieties was carried out selectively.
Three groups of non-camptothecin compounds with four to five fused rings have been designed and synthesized.
Modified compounds with two additional hydrophobic groups exhibited a better regulatory performance.
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