Sentence examples for compounds with enhanced from inspiring English sources

Further exploration of the central phenyl ring led to compounds with enhanced anti-proliferative activity.

This may be achieved by identifying compounds with enhanced potency for the inactivated state of Cav2.2.

This screen yielded 15 compounds with enhanced potency for SIRT2 inhibition and 11 compounds having SIRT2 inhibition equal to reference compound AK-1.

On the other hand, the DNA binding study is also useful in drug designing and synthesis of new compounds with enhanced biological properties.

Inorganic organic nanocomposites have unlocked new opportunities in the design of innovative materials and compounds with enhanced and unique properties, based on soft chemistry.

A major challenge for food and pharmaceutical industries is the engineering of nanostructures that can efficiently encapsulate bioactive compounds with enhanced physical and chemical stability, and high load.

The experimental validation was in good qualitative agreement with our theoretical calculations, while also a 6-dibromophenyl-substituted compound with enhanced inhibitory effect on EGFR compared to the reference ligand was obtained.

In this study, we utilized a prototypic next generation Hsp90 inhibitor, EC154, representing a novel synthetic compound with enhanced potency and diminished toxicity relative to 17-AAG.

This task was undertaken with the aim to obtain new compounds with an enhanced antiproliferative activity and, possibly, a different specificity with respect to the original (lead) compound.

These efforts led to the compound 4k, with enhanced CDK8 inhibitory activity and no apparent potential for time-dependent CYP3A4 inhibition (CDK8 IC50: 2.5 nM; CYP3A4 TDI: 99% compound remaining).

This strategy led to the identification of lead compound 9 with enhanced enzyme and cellular potency, while maintaining good selectivity over a number of kinases.