Sentence examples for compounds with distinct from inspiring English sources

Structure activity relationship studies and further structural elaboration afforded compounds with distinct activity profiles.

Flavor creation did not take its present form until the development of organic chemistry, in the early nineteenth century, when scientists began to identify volatile chemical compounds with distinct aromas.

Protocol validity was verified through simulations with a range of PK parameters in compartmental models as well as data comparison for nine compounds with distinct PK profiles.

A high through-put screen for inhibitors of Cdk5-mediated phosphorylation of tau resulted in three compounds with distinct mechanisms of action.

In order to design compounds with distinct antiviral properties, we prepared new compounds with modifications on the imidazole and pyrimidine rings.

Our polymeric system, which can administer multiple compounds with distinct kinetics, provides prolonged action and less invasive transscleral administration, and is expected to provide new tools for the treatment of posterior eye diseases with new therapeutic modalities.

In the present study, we investigated if gene expression profiling could be used to discriminate compound classes with distinct modes of action (MoA) using the EST protocol.

A phase 2 trial is ongoing at our centre with the fully human monoclonal antibody directed against TGF β receptor ALK1, PF03446962 (Pfizer Inc, La Jolla, CA, USA), a compound endowed with distinct antivascular activity, as second-line therapy in UC (ClinicalTrials.gov, number NCT01620970).

To understand how these properties influence bacterial permeability, we have developed a systematic approach to evaluate the penetration of diverse compounds into bacteria with distinct cellular envelopes.

Keeping that in mind, Holland and his team designed a new compound with two distinct properties found in nitrogenase: large shielding groups of atoms that prevented undesired reactions, and a weak iron-sulfur bond that could break easily upon the addition of electrons.

Data marked by ChEMBL as duplicates from earlier publications were discarded as these may be reference compounds with a structure distinct from the rest of the assay.