Sentence examples for compounds with better from inspiring English sources
Various thiourea derivatives have been used as starting materials for compounds with better biological activities.
In which, nine compounds with better antitumor activities were further tested for their PLK1 inhibitory activity.
Exploring the reactivities of such systems leads to the design of novel compounds with better reactivities.
Through virtual screening of known antimalarials from ChEMBL bioassay database, we mapped 10 compounds with better affinity towards PfGCN5.
These properties were also evaluated through the lipophilic and electrostatic potential maps, respectively, considering the compounds with better biological profile.
However, non-specific inhibition and drug resistance warrants the discovery of new anti-herpetic compounds with better therapeutic profile or different mode of action.
To overcome this problem, the engineers altered the rubber chemically to produce a rubber compound with better grip in hard driving.
In addition to these studies, we also investigated the methemoglobinemia potential and the feasibility of formation of the hydroxylated derivatives of NPC1161, a developmental antimalarial compound with better efficacy and lower toxicity.
After in silico screening of a library of ∼18,000 purchasable compounds, twenty-five of the top-ranking compounds all with better scores for binding energy and steric complementarity than orange G, were selected for experimental validation.
In order to search for novel leading compounds endowed with better antitumor activities and less neurotoxicities, a series of harmine derivatives were designed and synthesized by modification of position-2, 7 and 9 of β-carboline nucleus, and their cytotoxic activities against human tumor cell lines were investigated.
Out of the drugs used, diacerein and risedronate (alone or combined with glucosamine) were the compounds with a better profile of effectiveness in ameliorating these early changes, showing a better anti-inflamatory effect (in cartilage and synovial membrane), improving the cartilage surface alterations and increasing bone density.
