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These indicate that any compounds which activate RAR may be a candidate to enhance the antitumor activity of EGCG.
We uncover six novel small-molecule lead compounds, which activate p53 and repress the growth of human cancer cells.
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By using two highly responsive HaCaT cell line clones (#7 and 18) harboring four or more copies of the genetic sensor, we identified a group of compounds which activated the sensor very potently.
In addition, it also suggests that SMT022357 modulates the utrophin levels by a different mechanism of action compared with AICAR, a small compound which activates PGC-1α and PPARβ/δ via AMP-activated protein kinase (AMPK), a nexus of skeletal muscle plasticity (63, 64).
Quil A (Quillaja) is extracted from the evergreen tree Quillaja saponaria as triterpenoid compounds [ 36], which activate Th cells, cytotoxic T lymphocytes and B-cells.
In conclusion, our data suggest that P. indica releases chemical compounds prior to a physical contact which activate stress and defense processes in the host (2 days).
Whatever the case, the search for compounds which can activate TFEB in muscle would benefit the development of a TFEB-mediated therapeutic approach.
Neuropharmacologists at San Diego's Neurosciences Institute have isolated a chemical in chocolate with a marijuanalike compound, the neurotransmitter anandamide, which activates the same cellular receptors as THC.
Now the team at Edinburgh University has found that the immune cells, known as macrophages, can release a compound called activin-A, which activates production of more myelin.
When applied, this compound induces chemical hypoxia, which activates KATP channels [24].
When applied, this compound decreases intracellular ATP production and induces chemical hypoxia, which activates KATP channels [18].
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