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Compounds were subjected to quality control (QC) analysis and their activity was confirmed using our initial screening assay.
These compounds were subjected to cytotoxic evaluation against different tumoural cell lines.
The synthesized compounds were subjected to basic cytotoxic and antimicrobial tests.
The compounds were subjected to assessment of their potential activities through calcium mobilization assays.
The latter compounds were subjected to a Lindgren oxidation to yield compounds 11 18.
Hit compounds were subjected to various drug-like filtrations and molecular docking studies.
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Pharmaceutical compounds are subjected to a range of unit operations during manufacture, many of which can lead to hydration and dehydration of the drug material with the potential for phase transformation.
The dataset of 102 compounds was subjected to docking in order to validate the QSAR results via GOLD docking suit [12].
This would create a so-called semi-coherent interface at which the two compounds are subjected to strain, although the role of strain on the ionic conductivity has been recently questioned [13, 14, 15].
To generate SARMs compounds are subjected to a systematic two-step fragmentation procedure yielding matched molecular pairs (MMPs).
The abundance of the 15 aroma compounds was subjected to PCA to visualize the proximity of strains (Fig. 2).
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CEO of Professional Science Editing for Scientists @ prosciediting.com