Sentence examples for compounds were much from inspiring English sources
The compounds were much less potent on mammalian protein prenyltransferases.
Biologically, FONs-photosensitizers from these compounds were much more phototoxicities to cancer cell than to normal cell without significant dark toxicity.
In addition, the microhardness values of the Mg Al Zn intermetallic compounds were much higher than those of the substrate and this would greatly contribute to the enhancement of wear resistance.
The 1a 1g compounds were much more actives than precursor series 2a 2g, for example, IC50 = 7.65 μM on Leishmania amazonensis and 10.14 μM on Leishmania chagasi (compound 1c) when compared to IC50 = 50.08 μM on L. amazonensis and 82.29 μM on L. chagasi (compound 2c).
In addition, while van der Waals energies of Cpd30-12 wequivalentlent for its interaction with the Stat3 SH2 domain and the Stat1 SH2 domain, the 5 selective compounds were much more favorable for their interaction with the Stat3 SH2 domain than with the Stat1 SH2 domain (Figure 3I).
The doses of various SU compounds were much higher than usually therapeutically used in T2DM.
The aromatase inhibitory activities of these compounds are much more potent than that for the lead compound resveratrol, which has an IC50 of 80 μM.
Some compounds are much less toxic than the natural product febrifugine and existing antimalarial drug chloroquine and are expected to possess wide therapeutic windows.
Some compounds are much less toxic than the natural product febrifugine and existing antimalarial drugs and are expected to possess wide therapeutic windows.
This response was clearly synergistic since the increase in the levels of these compounds was much greater in the presence of both elicitors than when they were used separately.
Cytotoxicity against HPAC cell line was evaluated, and two of them exhibited comparable potency to kazusamycin A. Hepatic toxicity of these designed compounds was much lower than that of kazusamycin A.
