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Several approaches aimed at designing new bioactive compounds were described during this meeting.
The structural characteristics of compounds were described wholly by a large amount of molecular structural descriptors calculated by DRAGON.
Design, syntheses and structure activity relationships of N-acetylated piperazine privileged structures containing MC4R agonist compounds were described.
In addition, in the GPCR, and PI data set compounds were described by their physicochemical properties.
Chemical compounds were described by Scitegic circular fingerprints (ECFP_6 type), [21, 42] calculated in PipelinePilot 8.5.0.200 [43].
Compounds were described by chemical features, which were used to represent kinases (i.e. each kinase had an active set of features and an inactive set).
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(These compounds are described in the section Fatty acid derivatives).
The synthesis and biological activity of the compounds are described.
The synthesis and SAR of these compounds are described.
All the compounds are described herein for the first time.
The design, synthesis and SAR of these compounds are described.
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