Sentence examples for compounds we identified from inspiring English sources

Taken together, these results indicate that the α,β-unsaturated natural compounds we identified increase TJ permeability via TRPA1 activation, and that the induction of reversible TJ permeability by capsaicin is mediated via TRPA1.

After screening ~5000 compounds, we identified 23 primary hit compounds that prevented the increased cell death in GLIS3−/− INS−GFP+ PP2-β cells (Supplementary Fig. 6c and Supplementary Table 8).

Following the rational design, synthesis, and in vitro biological evaluation of several such compounds, we identified a reversible E1 inhibitor (4b).

Among the novel small compounds we identified with activity on hESC are several steroids that promote hESC differentiation and the antihypertensive drug, pinacidil, which affects hESC survival.

From our first round of compounds, we identified 2- hydroxyimino -3-phenylpropanoic acid as a potent CtBP inhibitor (IC50 = 0.2- hydroxyimino -3-phenylpropanoic

A model describing the binding modes of these hit compounds to hAMCase was constructed, and we discuss the structure activity relationships of the compounds we identified, suggested by the model and the actual inhibitory activities of the compounds.

In a proof-of-principle pilot screen of 2000 compounds, we identify the glutamine analogue, acivicin, a chemical with known activity against human tumour cells, as a potent and specific inhibitor of Drosophila tumour formation.

The compound we identified inhibits zebrafish embryo growth at a specific cell cycle phase, reduces mammalian CDK2 activity as well as tumor cell proliferation in vitro and in vivo.

For each compound we identified a set of functional annotations that were enriched.

Briefly, for each compound, we identified the set of genes exhibiting altered mRNA abundances at padjusted < 0.05.

During visual inspection of the clustering results, we noticed that: 1) some clusters contained compounds that appeared to have relatively little structural similarity, or 2) sometimes compounds that we identified as having structural similarity, were found in different clusters.