Sentence examples for compounds to specifically from inspiring English sources

The types of ERs and their signaling mechanisms identified in HCVECs could potentially be applied for developing estrogen-like compounds to specifically bind to a subtype of ERs with greater specific action on the cerebral arteries, without the estrogen-dependent side effects on the reproductive organs.

Subtypes of ERs and their signaling mechanisms identified in HCVECs could be applicable for developing estrogen-like compounds to specifically bind to a subtype of ERs with greater specific action on the cerebral arteries, without the estrogen-dependent side effects on the reproductive organs, to prevent cerebral aneurysm formation in menopausal and postmenopausal woman.

This is a crucial enzyme in the steroidal cascade and its inhibition results in major side-effects, as a result, the ability of compounds to specifically inhibit enzymes such as AR but not CSCC would be an important factor in the drug design process.

The homing principle by probe lipidation might also work for selective administration of cytotoxic compounds to specifically reduce tumor mass.

Potential renal and otic adverse effects associated with gentamicin exposure are well documented, prompting the search for other compounds to specifically induce read-through of nonsense mutations.

We suggest that the homing principle via probe lipidation might also work for selective administration of cytotoxic compounds to specifically reduce tumor mass.

In this context, promiscuity is defined as the ability of a compound to specifically interact with multiple targets (as opposed to non-specific binding effects).

Therefore, compounds able to specifically disrupt TcTIM but not Homo sapiens TIM (hTIM) dimer interface could become selective antichagasic drugs.

Therefore, to exclude false positives we validated the compounds' ability to specifically suppress 3Dpol activity with fluorescently labeled primer-extension assays.

This implied the selection BBB-permeating compounds known to specifically inhibit the target without affecting normal brain function.

Oblimersen sodium (G3139, Genasense, Genta Inc ,Berkeley Heights, NJ) is an antisense oligonucleotide compound designed to specifically bind to the first six codons of the human bcl-2 mRNA sequence, resulting in degradation of bcl-2 mRNA and subsequent decrease in Bcl-2 protein translation.