Sentence examples for compounds to avoid from inspiring English sources

By studying where exactly in the DNA sequence those mutations occur, and examining how Gleevec binds to the tumour-promoting protein that results, chemists have designed new compounds to avoid these problems.Two of these compounds, Sprycel (dasatinib) and Tasigna (nilotinib) have been used for several years to treat patients whose disease has progressed even though they were taking Gleevec.

For example, excluding highly connected compounds to avoid currency compounds may also exclude compounds that play a significant role in pathways (e.g., pyruvate).

The results of the work highlight the importance of using internal spiking standards (performance reference compounds) to avoid false non-detection results in passive sampler applications.

In many ways medicinal chemistry provides a bridge between biology and chemistry, identifying novel compounds that modulate a biological response and thusproviding the tools to investigate biological processes, subsequently optimizing those compounds to avoid undesired interactions with other biological systems.

Our data are compatible with the lactone rings of 14-membered and 16-membered macrolides adopting different conformations, enabling the latter compounds to avoid a steric clash with 2058G.

This rule has been in place since at least September 2008 when, according to a leaked classified report, ISAF introduced a tactical directive that "specifically called for limiting airstrikes on compounds to avoid civilian casualties when ISAF forces are not in imminent danger".

It is noteworthy that the reference complexes for PADIF based scoring were selected in a way that the respective molecules were not too similar to the docked compound to avoid bias and to show the method's broad applicability.

We can be sure that the enhanced electrochemical performance is due to the core-shell structure, which interconnected GNS and nickel-plated layer act as buffer compound to avoid the excessive volume expansion and the electrode pulverization.

This temperature measurement was repeated 3 hours after injection of compound (to avoid interference from stress-induced hyperthermia early after injection).

Adsorption experiments with different amounts of probe compounds and nanoparticles allowed establishing the minimum concentration of each probe compound required to avoid its complete adsorption by a specific NPs concentration in order to perform correct quantification of the nanomaterial surface activity, especially when simultaneous adsorption of multiple components is carried out.

In compound 1, to avoid steric hindrance between –COOCH3 and –OCH2CH3 (Fig. 3), the dihedral angle between H-6 and H-5 were changed, resulting in a large coupling constants (J = 8.4 Hz) for H-6/H-5 itsits 1H NMR spectrum, which were different from those of two other compounds.