Sentence examples for compounds to attenuate from inspiring English sources

Thus, partial TRPV1 agonists might be useful in anti-inflammatory and analgesic compounds to attenuate capsaicin's fiery sting.

Second, the inhibitory actions reported here for decursin and DA against estrogen-induced signaling events and cell proliferation in the MCF-7 cell model highlight potential specificity for these compounds to attenuate breast cancer risk in premenopausal women.

The present study was designed to examine the ability of curcumin, a natural polyphenolic compound, to attenuate acute AN-induced lipid peroxidation in the brain and liver of rats.

Understanding the precise molecular mechanism whereby ELN compounds modulate the γ-secretase activity would pave the way to develop a potentially safe and effective compound to attenuate β-amyloidosis in AD.

Both compounds failed to attenuate the ROS signals in any of the assays, suggesting that neither XOD nor uncoupled NOS are relevant sources of ROS in our cell models under the conditions used.

Novel compounds with potential to attenuate or stop the progression of Alzheimer's disease (AD) from its presymptomatic stage to dementia are being tested in man.

A number of compounds with potential to attenuate the progression of Alzheimer's disease (AD) from a presymptomatic stage to dementia - that is, drugs intended for secondary prevention of dementia due to AD - are currently undergoing testing in man [ 1, 2].

Moreover, selected compounds demonstrated the ability to attenuate the expression of the angiogenic markers (viz. MMP-9 and VEGF) in MDA-MB-231 cells at sublethal concentrations.

One of the compounds, CP2, was found to attenuate Aβ-induced toxicity in primary cortical neurons (Maezawa et al., 2006) and reduce Aβ aggregation in 5 × transgenic animal model of familial AD (Hong et al., 2009).

In the present study, 4OGOMV, a natural compound, has been shown to attenuate SAH-induced IL-1β and MCP-1 expression at the initial stage of SAH.

Certain nutritional compounds, however, have the potential to attenuate protein aggregation, directly or indirectly.