Sentence examples for compounds to act from inspiring English sources
In this study, we present a computer-aided approach to investigate a set of 32 recently synthesized chalcone and chalcone-like compounds to act as antileishmanial agents.
The ability of these compounds to act as antagonists to the androgen receptor was investigated and several were found to have potent activity in vitro.
The ability of these compounds to act as antagonists of the androgen receptor was investigated and several were found to have potent activity in vitro and in vivo.
These results suggested that the ability of these compounds to act as intercalating agents and Topo I inhibitors was related to the antitumor activity.
Rational drug discovery produces drug leads either by designing compounds to act against a particular biochemical target or by screening compounds until identifying candidates that act against the target's function.
These results demonstrate that the C-replaced BN nanosheet models are good compounds to act as sensitive sensors and absorbers of the NH2NO2 molecule.
On the other hand, the proximity between the oxydryl of the DNA 5′end and the two close oxygen atoms, acting as efficient hydrogen acceptors, explains the ability of the compound to act as an enhancer of the enzyme religation rate.
Moreover, the graphical results suggest that a compound to act as an OSC inhibitor should satisfy more structural requirements than those necessary to be successful as an SHC inhibitor.
Methyl substitutions on C-1 (R1-aminopropan-2-ol and S1-aminopropan-2-ol) diminished the ability of the compound to act as a substrate, but to varying degrees in a stereospecific fashion.
Measurements were carried out after addition of Oligo, FCCP, and rotenone/myxothiazol at concentrations of 0.75 μM for each compound to act as an ATP synthase inhibitor, respiratory chain uncoupler, and mitochondrial respiration inhibitors, respectively.
To explore the potential of each compound to act as a substrate for ShhN cholesterylation, HEK 293a cells stably transfected to overexpress Shh (HEK293a Shh+) were treated with 5 μM of each compound for 16 hours to allow metabolic probe incorporation.
