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The cytotoxicity of the obtained compounds can be important in narrowing the search for new, more cytotoxic molecules and can make these compounds the subject of great interest for further investigation.
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Synthesis, SAR and PK profile of these novel compounds constitute the subject matter of this Letter.
The risks were compounded because the subject of unfaithfulness is frequently taboo within relationships.
The challenge of finding photographs for the series, Ms. Gohl said, was compounded by the subject matter itself.
In these systems, the role of surface active compounds has been the subject of many investigations using a wide range of techniques.
The interactions of HAs with organic compounds have been the subject of intensive study for several decades.
The properties and applications of these compounds have been the subject of a number of general and specialized reviews (Rives 2001; Braterman et al. 2003; Zümreoglu-Karan and Ay 2012).
These compounds have been the subject of clinical trials that confirmed their clinical efficacy without the cardiovascular side effects commonly associated with triptans [4,5].
None of the submissions involves a compound that is the subject of an active investigational new drug (IND) or new drug application (NDA).
The latter compound has been the subject of a phase I clinical trial which has thus far only been published in abstract form [ 120].
The role of this distinct response to the elicitor and differences in accumulation of a specific defense compound will be the subject of future analysis in an ecological context.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com