Sentence examples for compounds that simultaneously from inspiring English sources
Gasparian, A. V. et al. Curaxins: anticancer compounds that simultaneously suppress NF-kappaB and activate p53 by targeting FACT.
Semivolatile particles are composed of compounds that simultaneously have meaningful concentrations in both vapor and condensed phases.
Importang breakthrough was the development of curaxins: anticancer compounds that simultaneously suppress NF-kB and activate p53 by targeting FACT [ 30, 125, 126].
That led drug firms to craft compounds that simultaneously trip PPAR gamma and PPAR alpha, potentially reducing the amount of heart-attack-causing fat in the blood.
Compounds that simultaneously inhibit VEGF and MET tyrosine kinase receptors are hence likely to be more effective anticancer agents than agents that target each of these receptors individually.
The research has suggested that β-ELE has synergistic effects and acts as a selective topoisomerase inhibitor, and several published studies have shown that compounds that simultaneously target both TOPO I and TOPO II α might have high antitumor activity.
Neem contains multiple active compounds that work simultaneously via different mechanisms (10– 10).
Thus, developing dual inhibitor compounds that will simultaneously inhibit COX and 5-LOX could enhance their individual anti-inflammatory effects and reduce the undesirable side-effects associated with NSAIDs, especially of the gastrointestinal (GI) tract (Fiorucci et al 2001).
On the other hand, if a large proportion of nodes in a network have to be modified in order to achieve recovery, then a different pharmaceutical strategy using compounds that can simultaneously affect multiple molecular targets should be followed.
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This shows that a compound that simultaneously blocks depolarizing currents (such as inward Na+ and Ca2+ currents) and repolarizing currents (such as outward K+ currents) to a similar extent may have little overall effect on AP duration.
