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Coenzyme, Any of a number of freely diffusing organic compounds that function as cofactors with enzymes in promoting a variety of metabolic reactions.
These studies define a novel class of anti-hypertrophic compounds that function through irreversible inhibition of CRM1-dependent nuclear export.
The total polyphenol concentration of extract includes in addition to the principal phenolic antioxidants all the compounds that function as hydrogen donors in the plant material.
The elucidation of the mechanisms by which growth hormone (GH) interacts with its receptor has facilitated the design of compounds that function as GH-receptor antagonists.
While the detection limits and resolution of charge coupled devices (CCDs) has increased greatly in recent years [2], there have been relatively few introductions of improved imaging compounds that function as light production centers within an animal subject in vivo.
Selective estrogen receptor modulators (SERMs) are a diverse group of nonsteroidal compounds that function as ligands for ERs.
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The difficult problem of preventing lithium dendrite formation on charging was solved in these cells by using specially selected carbon powders as a base in which to insert lithium ions to form a weak compound that functions as a high-voltage, high-energy-density anode.
Glycerin is a simple organic compound that functions as a humectant.
Alpha-lipoic acid (ALA) is a naturally occurring dithiol compound that functions as an essential cofactor for mitochondrial bioenergetic enzymes [ 6].
Nevertheless, using our approach, we were able to identify one compound that functions both as an antiviral and as a helicase inhibitor.
We hypothesized that a high throughput screen (HTS) aimed at identifying compounds that broadly function as pro-apoptotic UPR stimulants might provide novel starting scaffolds for further development.
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