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"Receptors are present because the body makes compounds that activate them".
Compounds that activate the RyR are potential inotropic agents to increase the Ca2+ transient and strength of contraction.
When we experience high temperatures, our cells release inflammatory compounds that activate a special kind of channel, TRPV1, in sensory neurons.
In conclusion, we have identified small molecule compounds that activate Wnt/β-catenin signaling in a highly cell-type specific manner.
To our knowledge, the present findings are the first to report the sensitizing and desensitizing properties of compounds that activate mechanosensitive pathways.
Additionally, the level of phosphorylated Nrf2 is increased by phenolic compounds that activate the PERK kinase [ 114].
Similar(19)
Compounds that activated human SXR also activated SXR in nonhuman primates, but fold induction relative to the vehicle was typically lower in these species.
Tian and colleagues used a high-throughput, cell-based screen to detect small compounds that activated the murine granulocyte-colony-stimulating factor (G-CSF) receptor.
Resveratrol (RES) is a chemical compound that activates SIRT1 deacetylase activity and suppresses the oxidative stress response in mammalian cells [ 27].
Dinoflagellates can produce the toxin brevetoxin, a cyclic polyether compound, and Ciguatoxin, a carbon polycyclic compound that activates the Na+ channel.
Together, our results demonstrate that fisetin, a compound that activates multiple, well-defined neuroprotective pathways, may provide a new approach to the treatment of AD.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com