Sentence examples for compounds suffer from from inspiring English sources
18F-labeled RGD compounds suffer from multistep and time-consuming synthetic procedures, which will limit their clinic availability.
Most of the known approaches to the synthesis of CF3-containing organic compounds suffer from serious drawbacks.
Several potent and selective A2BAdoR antagonists have been reported in literature, however most of the compounds suffer from poor pharmacokinetic profile.
Research programs aimed at developing small-molecule antagonists of the Eph receptors are still in their initial stage as available compounds suffer from pharmacological drawbacks, limiting their application in vitro and in vivo.
Many promising compounds suffer from poor physiochemical properties leading to poor solubility and biodistribution.
However; these lipophilic compounds suffer from poor aqueous solubility which limits the OS oral bioavailability and therapeutic applications.
However, these compounds suffered from poor in vitro pharmacokinetic (PK) profiles and they have a similar structure/SAR to inhibitors of human soluble epoxide hydrolase (sEH) enzymes.
The first 18F tracer with tau binding was 18F-FDDNP, although the compound suffered from a lack of selectivity (Kepe et al. 2013).
However, it is time consuming, requires the manipulation of radioactive compounds, suffers from a lack of sensitivity, does not allow simultaneous analysis nor more importantly quantification and does not allow us to determine the percentage of multiple rRNA molecules that are methylated at a given position.
The preparation of mixtures of multiple candidate ligands via the pooling of individual compounds suffers from the cost and time required for synthesizing individual compounds, but the composition ratios of candidate ligands in these mixtures can be rigorously controlled.
In general, data curation involves steps like the removal of duplicates, compounds with wrong Lewis structures, compounds for which descriptors could not be calculated, and in case of experimentally measured data the removal of compounds which suffer from errors caused by the measurement process.
