Sentence examples for compounds progress from inspiring English sources

A representative 'test cascade' for discovering new small-molecule inhibitors of cancer targets is shown in Figure 2. As a consequence of extensive in vitro testing, comparatively small numbers of prioritised compounds progress to examination in vivo (Collins and Workman, 2006).

This indicated a loss of vitality that gradually expanded from the tip cell to the basal cells of LGT when the accumulation of the compounds progressed.

The success rate for advancing from one phase to another is low, and the number of compounds progressing to regulatory review is among the lowest found in any therapeutic area.

We analyzed both trial activity and, where possible, unique compound progress through the AD pipeline.

The results are presented in an easily interpretable odds ratio so that teams can readily compare compounds and progress potential clinical candidates to the necessary rodent in vivo studies.

In order to support the selection of compounds to progress in the murine malaria model, the in vitro potency was also assessed against P. berghei (rodent parasite).

These in vitro assays act as important filters removing in-active compounds to progress only the most potent ones to in vivo screening.

Many other compounds are progressing through preclinical studies and are nearing human trials.

Electrochemical reduction of carbonyl compounds has progressed considerably during the past 20 years, not only in theory but also in application.

In the past decade, ten compounds have progressed into the clinical development pipeline, including six new compounds specifically developed for tuberculosis.

These compounds were progressed into potency determination studies using 10-point dilution curves.