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The data were used to construct dose response curves for the evaluation of absolute IC50 (n = 12) We first investigated the effect of the compounds on cell proliferation during one treatment cycle (Fig. 1a c).
The effect of compounds on cell vitality was determined by MTT assay in various cells.
The effects of our synthesized compounds on cell viability toward the MCF-7 and MDA-MB-468 breast cancer cell lines were evaluated.
The obtention of mutants deficient in biosurfactant secretion confirmed the influence of these compounds on cell motility and hence on cell attachment.
The effect of the synthesized compounds on cell proliferation was evaluated by MTT assay in three human cancer cell lines: MDA-MB-468, SK-BR-3 and HCT-116.
(D) Effect of the two compounds on cell survival when the HeLa cells were treated by various stressors.
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New test rapidly evaluates the effect of drugs and potentially toxic compounds on cells.
Just randomly sprinkling compounds on cells and measuring amyloid levels requires both time and luck to get a good hit.
BenevolentBio tested the five compounds on cells cloned from ALS patients' own cells.
There are two methods which are commonly used to interrogate the action of compounds on cells.
In both cell lines, decreased ERK1/2 phosphorylation was associated with these cellular effects, whereas the effects of these compounds on cell-cycle regulatory proteins cyclin D1, P21CIP1 and P27KIP1 appeared cell line specific.
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