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As mentioned above, the legumes produce secondary compounds of an irritating or poisonous nature that provide protection against predators.
Computer-aided drug design scaffold hopping strategies were utilized to identify new classes of CB2 agonists when compounds of an established series with low nanomolar potency were challenging to optimize for good drug-like properties.
This is especially the case if all compounds of an entire region of the data set are removed from the model building set and split away into the test set.
3- 1-naphthoyl -1H-indole is an example of a compound with low 2D similarity to the target compounds of an immunoassay, but which nonetheless has good cross-reactivity.
Although the recall performance of a query is highly dependent on the enrichment of similar active compounds in the test set, it is likely that the higher structural diversity of active compounds of an activity class makes it more difficult to efficiently retrieve active hits when the number of hits is limited.
Spring of 1945: As the allied forces were closing in on Nazi Germany, young men from both the US and Soviet armies were reaching the fenced boundaries of military compounds of an extraordinary nature.
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Officers live behind high walls, in manicured compounds of a luxury unimaginable to the average Pakistani.
By the early 1800s it became clear that the earths, formerly considered to be elements, were in fact oxides, compounds of a metal and oxygen.
This method starts from lower molecular weight compounds of a family of species and proceeds to higher molecular weight compounds.
An iteration starts by applying reaction rules to each of the compounds of a source set.
All the modifications attempted on diflunisal are clearly detrimental and spoil its inhibitory potency (compounds of "a" series).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com