The broad negative associated regions between 3259 and 2989 cm−1 correspond to the O-H stretching vibration of various compounds and, as mentioned earlier, their interpretation is difficult.
This problem is compounded by the issue of patient variability mentioned earlier as it is easy to adhere to the treatment protocol with some patients whereas with others it is much more difficult.
As a result, pharmaceutical companies have developed a range of earlier and cheaper in-house assays, designed to evaluate whether compounds are likely to run into problems with the regulatory requirements mentioned earlier (Pollard et al., 2008).
As mentioned earlier, new data are available for this compound but have not been evaluated for setting OELs.
As mentioned earlier, correlations have been drawn between a compound's melting point and its Log of solubility; however, the literature remains sparse when making comparisons to cocrystals.
As mentioned earlier, the anatomical region within the RT where a particular compound preferably deposits is partly determined by its water solubility (Shusterman 2003).
As mentioned earlier, only a single kinase, namely NEK7, was not inhibited by any compound, and therefore did not share any active compounds either.
In particular, a descriptor at the root node will be used to classify every new compound, since it occurs in all paths from the root to any leaf node, as mentioned earlier.
As mentioned earlier, ABC transporters are involved in uptake of high molecular weight pharmacological agents including xenobiotic compounds [ 44].
As mentioned earlier, the log Kt:p values of different tissues are unknown for the large majority of compounds in the Vss-target dataset.
