Sentence examples for compounds library from inspiring English sources

To identify compounds that inhibit the canonical Wnt signaling pathway, two hundred ent-kauranoids from a natural compounds library were screened using HEK293 cells that were stably co-transfected with Topflash, renilla reporters and wnt3A, namely HEK293W cells [14].

This strategy involves three steps: The design and the synthesis of a fluorescent compounds library using known chemical scaffolds that exhibit low specificity for any given protein; Screening the fluorescent compounds library by fluorescence polarization measurements in order to successfully fish out at least one probe.

Sun et al. recently identified, through a high throughput screening against a natural compounds library, nine AdipoRs agonists [ 160].

RO9021 was identified following extensive medicinal chemistry optimization of a lead identified from high-throughput screening of Roche's proprietary chemical compounds library.

In this study, we used serum free medium to mimic the low nutrient environment to screen active compounds from the Garcinia compounds library.

We also identified eight compounds (library pages 48 54, 57) with mass spectra containing similar fragmentation to DDE, but with a larger number of chlorines (six to eight).

This chemistry provides a new compound library with potential activity for biomedical screening.

As such, considering multiple structure representations provides a broader picture of the diversity of the compounds libraries.

Huang, R. et al. Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway.

Application of this novel strategy for compound library design provided enhanced hit rates in small compound libraries for structurally similar proteins.

A high-throughput microfluidic screen of a compound library identified 18 compounds that substantially inhibited binding of RNA by NS4B.