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Inspired from geldanamycin, the synthesis of a new series of 20-membered macrocyclic compounds is developed.
A method of characteristics model for compositional simulation of groundwater contamination and remediation involving organic compounds is developed.
In this study a numerical groundwater reactive transport model of a shallow groundwater aquifer contaminated with volatile organic compounds is developed.
In the present paper, a new family of non-symmetrical monocationic compounds is developed including a 3-aminophenol moiety, bound to 4- dimethylamino)- or 4- dimethylaminoyl)pyridinium cationic heads through several linkers.
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Cocrystals will raise IP and regulatory questions as more of these compounds are developed, moved later into development, and eventually marketed.
A new GC MS methodology to determine quantitatively the volatile aroma compounds was developed.
A linear classification function to discriminate the anti-inflammatory from the inactive compounds was developed.
An analytical method for simultaneous determination of both compounds was developed using solvent desorption.
DACS (Database of available chemical compounds) was developed to design a HTS collection or focused libraries for the FMP Screening Unit.
Design issues are crucial in the evaluation of the potential efficacy and tolerability of compounds being developed for clinical use.
The simultaneous quantification of the compounds was developed using high-performance liquid chromatography with diode array and fluorescence detectors.
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